Dextromethorphan/Guaifenesin

(dex-troe-meth-or-fan/gwye-fen-e-sin)

Other names for this medication: Cough Tablets for Dogs and Cats, Mucinex DM, Robitussin DM

Used to treat cough in dogs and cats

•May be given with or without food

•Do not split or crush extended-release tablets.

•There are many dextromethorphan/guaifenesin products available. Only use products recommended by your veterinarian.

•Common side effects include vomiting, diarrhea, lack of energy, and uncoordinated movement.

Description

•Combination cough medication

‐Dextromethorphan is a cough suppressant.

‐Guaifenesin is an expectorant that helps clear mucus out of airways and lungs.

•Available as tablets, extended-release tablets, capsules, and oral liquids

•There are many dextromethorphan/guaifenesin products available. Only use products recommended by your veterinarian.

Uses

This medication is available as a product labeled for relief of cough in dogs and cats, but it has not been approved by the FDA. However, other products are FDA-approved for use in humans that may be used in animals (extra-label) at the discretion of your veterinarian.

Before this medication is given

No medication is 100% safe in all patients. Discuss with your veterinarian:

•Any other medications or supplements your animal is taking

•Any conditions or diseases your animal currently has or has had in the past

•Any side effects your animal has had to medications in the past

•The risks of using this medication if your animal is pregnant or nursing

Warnings for animals

•Products containing acetaminophen must NEVER be used in cats. Acetaminophen is deadly in cats.

•Do not use:

‐In animals that are allergic to it

‐In dogs or cats less than 3 months old

‐In dogs or cats that weigh less than 5 pounds

•Use with caution in animals:

‐With a chronic cough

‐With excess secretions

‐With prolonged depression (eg, tiredness, incoordination)

‐With a fever

‐With liver disease

‐With atopic dermatitis

‐Wearing an amitraz flea collar or taking medications that can affect serotonin, such as antidepressants or selegiline

•Certain medications are not allowed in some animal competitions. Check rules and regulations when your animal is taking a medication.

Warnings for humans

•Wash your hands after handling any medication.

How do I give this medication?

•Give with or without food. Giving with food may help prevent stomach upset.

•Do not split or crush extended-release tablets.

•Measure liquids using an oral syringe, medicine cup, or dosing spoon. Do not use household measuring devices.

Give exactly as your veterinarian has prescribed. Always follow the instructions on the prescription label.

Side effects

Common – contact your veterinarian if any of these signs are severe, continue to occur, or worsen over time:

•Vomiting or diarrhea

•Lack of energy

•Excitement or high energy levels

•Uncoordinated movement

Severe – stop the medication and contact your veterinarian immediately if you notice any of these signs:

•Collapse

•Muscle rigidity

Very rarely, this medication can cause a condition called serotonin syndrome. This happens when too much serotonin builds up in the body. Potential signs include rigid muscles, muscle tremors, restlessness, panting or pacing, agitation, enlarged pupils, loss of coordination, disorientation, or seizures. Contact your veterinarian immediately if you notice any of these signs. Giving multiple medications that affect serotonin at the same time increases the risk for serotonin syndrome.

How will I know it's working?

•Your animal should start feeling better in 1 to 2 hours.

Contact your veterinary clinic if your animal’s signs worsen or do not improve.

How long will the medication effects last?

•This medication will stop working within 24 hours of the last dose.

How long do I give it for?

This medication can be given for different lengths of time. Give it for as long as your veterinarian tells you. You may need to refill the prescription.

Overdose

Signs of overdose may include uncoordinated movement, seizures, or difficulty breathing. If you witness or suspect an overdose, call your veterinarian or an animal-specific poison control center (consultation fee applies):

•ASPCA Animal Poison Control Center: (888) 426-4435

•Pet Poison Helpline: (855) 764-7661

Have the product or label with you if possible.

Missed dose

In most cases, if you miss a dose:

•Give it when you remember, then return to the regular dosing schedule.

If it is close to the time for the next dose:

•Skip the missed dose.

•Give the next dose at the next scheduled time.

•Continue the regular dosing schedule.

If you are unsure, call your veterinary clinic. Do not double-up or give extra doses.

Storage

•Store in the original container at room temperature.

•Keep out of reach of children and animals.

Disposal

Do not flush this medication down the toilet or wash it down the sink. Options for disposing of unused or expired medications include:

•Drug take back sites: This is preferred whenever possible. To find a site near you, contact your local law enforcement or waste management authorities.

•Home disposal: Mix the medication in with coffee grounds or kitty litter, seal the mixture in a plastic bag, and throw it away in the trash.

Do not save leftover medication or give it to others to use.