Levetiracetam is used to prevent seizures.

•May be given with or without food

•Do NOT split or crush extended-release tablets.

•The most common side effects are lack of energy, uncoordinated movement, and decreased appetite.

•Do not stop this medication suddenly.

Description

•Anticonvulsant

•Available as immediate-release tablets, extended-release tablets, and oral liquids

Uses

This medication is not FDA approved specifically for animals, but it is approved for use in humans. At the discretion of your veterinarian, this medication may be used in other species (extra-label), such as for:

•Prevention of seizures in dogs, cats, and other species with epilepsy

Before this medication is given

No medication is 100% safe in all patients. Discuss with your veterinarian:

•Any other medications or supplements your animal is taking

•Any conditions or diseases your animal has now or has had in the past

•Any side effects your animal has had to medications in the past

•The risks of using this medication if your animal is pregnant or nursing

Warnings for animals

Do not use:

•In animals that are allergic to it

Use with caution:

•In animals with kidney disease

Certain medications are not allowed in some animal competitions. Check rules and regulations when your animal is taking a medication.

Warnings for humans

•Wash your hands after handling any medication.

How do I give this medication?

•Give with or without food.

•Do NOT split or crush extended-release tablets.

‐Extended-release tablets slowly release medication over time.

‐Breaking the tablets releases medication faster than intended and can cause side effects.

•Measure liquids using an oral syringe, medicine cup, or dosing spoon. Do not use household measuring devices.

Give exactly as your veterinarian has prescribed. Always follow the instructions on the prescription label.

Side effects

Common – contact your veterinarian if any of these signs are severe, continue to occur, or worsen over time:

•Lack of energy or drowsiness

•Uncoordinated movement

•Decreased appetite, vomiting, or drooling

Severe – stop the medication and contact your veterinarian immediately if you notice any of these signs:

•Changes in behavior

•Complete loss of appetite

How will I know it's working?

•This medication will start working within a few hours, but you will not be able to see its effects.

•In some animals, this medication may stop working well over time. Contact your veterinarian if your animal’s seizure frequency increases.

How long will the medication effects last?

•This medication will stop working within 24 hours of the last dose.

•It may last longer if your animal has reduced kidney function.

How long do I give it for?

This medication can be given for different lengths of time but is often a lifelong medication. Give it for as long as your veterinarian tells you. Make sure to refill the prescription to avoid interruptions in treatment.

Do not suddenly stop giving this medication.

•When discontinuing, the dose needs to be decreased gradually over time to prevent side effects and withdrawal seizures.

•Your veterinarian will provide tapering instructions.

Overdose

If you witness or suspect an overdose, call your veterinarian or an animal-specific poison control center (consultation fee applies):

•ASPCA Animal Poison Control Center: (888) 426-4435

•Pet Poison Helpline: (855) 764-7661

Have the product or label with you if possible.

Missed dose

In most cases, if you miss a dose:

•Give it when you remember, then return to the regular dosing schedule.

If it is close to the time for the next dose:

•Skip the missed dose.

•Give the next dose at the next scheduled time.

•Continue the regular dosing schedule.

If you are unsure, call your veterinary clinic. Do not double-up or give extra doses.

Storage

•Store in the original container at room temperature.

•Keep out of reach of children and animals.

Disposal

Do not flush this medication down the toilet or wash down the sink. Options for disposing of unused or expired medications include:

•Drug take back sites: This is preferred whenever possible. To find a site near you, contact your local law enforcement or waste management authorities.

•Home disposal: Mix the medication in with coffee grounds or kitty litter, seal in a plastic bag, and throw away in the trash.

Do not save leftover medication or give it to others to use.